Felodipine

• Catalog No.: Bio-0040
• CAS Number: 72509-76-3
• M. F.: C18H19Cl2NO4
• M. W.: 384.25376

SYNONYMS

• IUPAC name: 3-ethyl 5-methyl (4S)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC Traditional name: 3-ethyl 5-methyl (4S)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• Synonyms: Plendil; Modip; Agon; Feloc; Hydac; Fensel; Plandil; Splendil

DATABASE IDS

• CAS Number: 72509-76-3

PROPERTIES

• Application(s): Antihypertensive agent
• Application(s): Vasodilator
• Application(s): Used to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina
• Mechanism of Action: Calcium channel blocker
• Mechanism of Action: Reversibly competes with nitrendipine and other calcium channel blockers for dihydropyridine binding sites
• Mechanism of Action: Blocks voltage-dependent calcium currents in vascular smooth muscle and cultured rabbit atrial cells, and blocks potassium-induced contracture of the rat portal vein
• Mechanism of Action: By blocking the calcium channels, inhibits the influx of extracellular calcium across the myocardial and vascular smooth muscle cell membranes and
• Mechanism of Action: results in a decrease of peripheral vascular resistance.

REFERENCES

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