NAMES AND DATABASE IDS
NAMES AND DATABASE IDS
Names Database IDs
IUPAC name
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2-[2-hydroxy-5-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol
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IUPAC Traditional name
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magnolol
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2-[2-hydroxy-5-(prop-2-en-1-yl)phenyl]-4-(prop-2-en-1-yl)phenol
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Synonyms
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5,5′-Diallyl-2,2′-biphenyldiol
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Magnolol
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5,5'-Diallyl-[1,1'-biphenyl]-2,2'-diol
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2
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2'-Bichavicol
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Magnolol
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CAS Number
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MDL Number
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PubChem SID
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PubChem CID
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DATA SOURCES
DATA SOURCES
All Sources Commercial Sources Non-commercial Sources
CALCULATED PROPERTIES
CALCULATED PROPERTIES
JChem
Acid pKa
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8.690145
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H Acceptors
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2
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H Donor
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2
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LogD (pH = 5.5)
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5.2102036
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LogD (pH = 7.4)
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5.1887584
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Log P
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5.210482
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Molar Refractivity
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83.7306 cm3
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Polarizability
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33.158566 Å3
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Polar Surface Area
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40.46 Å2
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Rotatable Bonds
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5
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Lipinski's Rule of Five
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false
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DETAILS
DETAILS
Selleck Chemicals
Sigma Aldrich
Selleck Chemicals -
S2321
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Research Area: Infection , Inflammation Biological Activity: Magnolol (2,2’-Bichavicol) is a bioactive compound found in the bark of the Houpu magnolia(Magnolia officinalis). |
Sigma Aldrich -
M3445
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Biochem/physiol Actions Bioactive plant component with antifungal,1 antibacterial2 and antioxidant effects.3 Magnolol also demonstrates anti-inflammatory activity by interferring with NF-κB signaling.4 |
REFERENCES
REFERENCES
From Suppliers
Google Scholar
PubMed
Google Books
- • Runeberg, J. et al., Acta Chem. Scand., 1957, 11, 1060; 1958, 12, 188
- • Clark, A.M. et al., J. Pharm. Sci., 1981, 70, 951, (props)
- • Wang, Y. et al., J. Chin. Chem. Soc. (Peking), 1982, 30, 215, (cryst struct)
- • El-Feraly, F.S. et al., J. Nat. Prod., 1983, 46, 493
- • Watanabe, K. et al., Planta Med., 1983, 49, 103, (isol, pharmacol)
- • Hattori, M. et al., Chem. Pharm. Bull., 1984, 32, 5010; 1986, 34, 158, (metab)
- • Ho, T.I. et al., CA, 1986, 105, 152803, (synth)
- • Teng, C.-M. et al., Thromb. Res., 1988, 50, 757, (pharmacol)
- • Wang, J.-P. et al., Naunyn-Schmiedeberg's Arch. Pharmacol., 1992, 346, 707, (pharmacol)
- • Tsai, T.-H. et al., Drug Metab. Dispos., 1994, 22, 518, (hplc, pharmacokinet)
- • Agharahimi, M.R. et al., J.O.C., 1995, 60, 1856, (synth, ir, pmr, cmr, ms)
- • Tsai, T.-H. et al., Neurosci. Lett., 1995, 186, 49, (pharmacol)
- • Kim, Y.-K. et al., Planta Med., 1996, 65, 291-292, (activity)
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PATENTS
PATENTS
PubChem Patent
Google Patent