tetradecanoic acid

• ChemBase ID: 5856
• Molecular Formular: C14H28O2
• Molecular Mass: 228.37092
• Monoisotopic Mass: 228.20893014
• SMILES: C(=O)(O)CCCCCCCCCCCCC
• Canonical SMILES: CCCCCCCCCCCCCC(=O)O
• InChI: InChI=1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)
• InChIKey: TUNFSRHWOTWDNC-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: tetradecanoic acid
• IUPAC Traditional name: myristic acid
• Synonyms: MYRISTIC ACID; C14:0 (Lipid numbers); 1-Tridecanecarboxylic acid; C14:0; NSC 5028; Myristic acid; Tetradecanoic acid; Myristic acid; Tetradecanoic acid; tetradecanoic acid; 十四烷酸; 肉豆蔻酸; 十四烷酸

Database IDs

• CAS Number: 544-63-8
• EC Number: 208-875-2
• MDL Number: MFCD00002744
• Beilstein Number: 508624
• Merck Index: 146333
• PubChem SID: 99444702; 24886048; 160969283; 24901314; 24886049; 24901313; 24896795
• PubChem CID: 11005
• CHEMBL: 111077
• Chemspider ID: 10539
• FEMA ID: 2764
• Wikipedia Title: Myristic_acid
• Council of Europe Number: 16
• Flavis Number: 8.016

CALCULATED PROPERTIES

JChem

• Acid pKa: 4.9520197
• H Acceptors: 2
• H Donor: 1
• LogD (pH = 5.5): 4.71164
• LogD (pH = 7.4): 2.9525049
• Log P: 5.3674455
• Molar Refractivity: 67.8816 cm^3
• Polarizability: 27.025951 Å^3
• Polar Surface Area: 37.3 Å^2
• Rotatable Bonds: 12
• Lipinski's Rule of Five: false

ALOGPS 2.1

• Log P: 6.1
• LOG S: -5.12
• Solubility (Water): 1.72e-03 g/l

PROPERTIES

Physical Property

• Melting Point: 52-54 °C(lit.); 53-56 °C; 53-56°C; 54.4 °C; 54.5 °C; 54.5°C
• Boiling Point: 250 °C/100 mmHg(lit.); 250.5 °C at 100 mmHg; 326°C; 326°C; ca. 326 °C at 1013 hPa
• Flash Point: >113 °C; >235.4 °F; 175°C(347°F); ca. 175 °C (Cleveland Open Cup)
• Density: 0.862; 0.8622 g/cm^3; ca. 858 kg/m3 at 60 °C
• Vapor Pressure: .0065 hPa at 20 °C
• Hydrophobicity(logP): 6.154
• Organoleptic: oily; waxy

Safety Information

• Storage Condition: 0°C
• RTECS: QH4375000
• European Hazard Symbols: Irritant (Xi)
• German water hazard class: nwg
• Risk Statements: 36/37/38; 38; R:36/37/38
• Safety Statements: 26-37; S:20-25-26-37/39
• TSCA Listed: 是
• GHS Pictograms: GHS07
• GHS Signal Word: Warning
• GHS Hazard statements: H315; H315-H319-H335; H319
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A; P305 + P351 + P338
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Storage Temperature: -20°C
• Regulation Compliance: EU Regulation 1334/2008 & 178/2002; FCC; FDA 21 CFR (172.210); FDA 21 CFR (172.860); FDA 21 CFR (173.340)

Pharmacology Properties

• Allergens: no known allergens

Product Information

• Purity: ~95%; ≥98.0% (GC); ≥98.5% (GC); ≥99%; ≥99.5%; ≥99.5% (GC); 95%; 95+%; 98%; 99-100%
• Grade: analytical standard; certified reference material; FG; Halal; Kosher; natural; NI; Sigma Grade; TECHNICAL
• Packaging: pkg of 1 g
• Shelf Life: (limited shelf life, expiry date on the label)
• Pharmacopeia Traceability: traceable to USP 1448990
• Linear Formula: CH3(CH2)12COOH

DETAILS

MP Biomedicals - 02102375

Technical Grade
Purity: ~95%
Crystalline

MP Biomedicals - 02100870

Crystalline
Purity: 99-100%

MP Biomedicals - 05216758

MP Biomedicals Rare Chemical collection

DrugBank - DB08231

Drug information: experimental

Sigma Aldrich - 153796

Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - PHR1124

General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO Guide 34.
Other Notes
Values of analytes vary lot to lot.
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - W276405

Packaging
1 kg in poly bottle
5, 10 kg in poly drum
1 sample in glass bottle
100 g in poly bottle
25 kg in fiber drum
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - 130087

Packaging
1 kg in poly bottle
5 g in glass bottle
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - 70079

Other Notes
Binding to serum albumin2
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - M3128

Biochem/physiol Actions
Myristic acid is a straight-chain 14-carbon fatty acid. Diets rich in myristic acid, along with lauric and palmitic acids, are associated with increased serum levels of low densisity lipoprotein cholesterol.
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.
包装
10, 100, 500 g in poly bottle

Sigma Aldrich - W276413

Packaging
1 kg in poly bottle
1 sample in glass bottle
5, 10, 25 kg in fiber drum
Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - 70080

Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.

Sigma Aldrich - 70082

Biochem/physiol Actions
Myristic acid is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation. Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions. Myristolyation of proteins affect many cellular functions and thus has implications in health and disease 1.