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2,6-diaminohexanoic acid hydrobromide

ChemBase ID: 132449
Molecular Formular: C6H15BrN2O2
Molecular Mass: 227.0995
Monoisotopic Mass: 226.03168973
SMILES and InChIs

SMILES:
C(CCN)CC(C(=O)O)N.Br
Canonical SMILES:
NCCCCC(C(=O)O)N.Br
InChI:
InChI=1S/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H
InChIKey:
MEXAGTSTSPYCEP-UHFFFAOYSA-N

Cite this record

CBID:132449 http://www.chembase.cn/molecule-132449.html

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NAMES AND DATABASE IDS

NAMES AND DATABASE IDS

Names Database IDs
IUPAC name
2,6-diaminohexanoic acid hydrobromide
IUPAC Traditional name
lysine hydrobromide
Synonyms
PDL
Poly-D-lysine hydrobromide
Poly-DL-lysine hydrobromide
多聚-D-赖氨酸 氢溴酸盐
多聚-D-赖氨酸氢溴酸盐
聚-DL-赖氨酸 氢溴酸盐

CALCULATED PROPERTIES

CALCULATED PROPERTIES

JChem
Acid pKa 2.7382863  H Acceptors
H Donor LogD (pH = 5.5) -5.9555907 
LogD (pH = 7.4) -4.978252  Log P -3.2145348 
Molar Refractivity 37.8095 cm3 Polarizability 15.365045 Å3
Polar Surface Area 89.34 Å2 Rotatable Bonds
Lipinski's Rule of Five true 

PROPERTIES

PROPERTIES

Physical Property Safety Information Product Information Bioassay(PubChem)
Apperance
lyophilized powder expand Show data source
MSDS Link
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
German water hazard class
3 expand Show data source
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter expand Show data source
Storage Temperature
-20°C expand Show data source
Suitability
suitable for cell culture expand Show data source
Sterility
γ-irradiated expand Show data source
Quality Level
PREMIUM expand Show data source
Mol. Weight
average mol wt 30,000-70,000 expand Show data source
average Mv >70,000 expand Show data source
average Mv 1,000-4,000 expand Show data source
mol wt >300,000 expand Show data source
mol wt ≥300,000 expand Show data source
mol wt 1,000-5,000 expand Show data source
mol wt 15,000-30,000 expand Show data source
mol wt 150,000-300,000 expand Show data source
mol wt 30,000-70,000 expand Show data source
mol wt 4,000-15,000 expand Show data source
mol wt 70,000-150,000 expand Show data source
Linear Formula
D-Lys-(D-Lys)/n-D-Lys · xHBr expand Show data source
D-Lys-(D-Lys)n-D-Lys · xHBr expand Show data source

DETAILS

DETAILS

Sigma Aldrich Sigma Aldrich
Sigma Aldrich - P6407 external link
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Analysis Note
Molecular weight based on viscosity.
Application
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
This product has a higher binding site density, but is more viscous than P7280. It is a poly-D-lysine that can be used with cells that digest poly-L-lysine polymers.
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
General description
Poly-lysine polymers are useful molecules to prepare surfaces for cell attachment. Poly-lysine polymers are available in L and D conformations. Poly-L-lysine polymers can be digested by some cell types, whereas poly-D-lysines are stable. Poly-lysine polymers from 70 to 300 kDa provide sufficient attachment site density for good cell adherence. However, higher molecular weight poly-lysine polymers are more viscous and difficult to work with.The choice of poly-lysine polymer for a specific cell type and application should account for the susceptibility of the polymer to digestion, the required attachment site density and the difficulty in handling.
Sigma Aldrich - P4408 external link
Analysis Note
Molecular weight based on viscosity.
Application
Poly-lysine with mol. wt. >30,000 is useful in promoting cell adhesion to solid substrates.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Sigma Aldrich - P7405 external link
Analysis Note
分子量基于粘度。
Application
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源。
Sigma Aldrich - P7280 external link
Analysis Note
分子量基于粘度。
Application
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
This product has a lowerer binding site density, but is less viscous than P6407. It is a poly-D-lysine that can be used with cells that digest poly-L-lysine polymers.
有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源。
General description
Poly-lysine polymers are useful molecules to prepare surfaces for cell attachment. Poly-lysine polymers are available in L and D conformations. Poly-L-lysine polymers can be digested by some cell types, whereas poly-D-lysines are stable. Poly-lysine polymers from 70 to 300 kDa provide sufficient attachment site density for good cell adherence. However, higher the molecular weight poly-lysine polymers are more viscous and difficult to work with.The choice of poly-lysine polymer for a specific cell type and application should account for the susceptibility of the polymer to digestion, the required attachment site density and the difficulty in handling.
Sigma Aldrich - P6403 external link
Analysis Note
Molecular weight based on viscosity.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Sigma Aldrich - P7886 external link
Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Sigma Aldrich - P0899 external link
Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.
Sigma Aldrich - P0296 external link
Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.
Sigma Aldrich - P1024 external link
Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.
Sigma Aldrich - P1149 external link
Analysis Note
Molecular weight based on viscosity.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.
Sigma Aldrich - 81358 external link
Application
Poly-lysine with mol. wt. >30,000 is useful in promoting cell adhesion to solid substrates.
Other Notes
Useful for promoting cell adhesion to solid substances1
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

REFERENCES

REFERENCES

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PATENTS

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