2,6-diaminohexanoic acid hydrobromide

• ChemBase ID: 132449
• Molecular Formular: C6H15BrN2O2
• Molecular Mass: 227.0995
• Monoisotopic Mass: 226.03168973
• SMILES: C(CCN)CC(C(=O)O)N.Br
• Canonical SMILES: NCCCCC(C(=O)O)N.Br
• InChI: InChI=1S/C6H14N2O2.BrH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H
• InChIKey: MEXAGTSTSPYCEP-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: 2,6-diaminohexanoic acid hydrobromide
• IUPAC Traditional name: lysine hydrobromide
• Synonyms: PDL; Poly-D-lysine hydrobromide; Poly-DL-lysine hydrobromide; 多聚-D-赖氨酸 氢溴酸盐; 多聚-D-赖氨酸氢溴酸盐; 聚-DL-赖氨酸 氢溴酸盐

Database IDs

• CAS Number: 73565-55-6; 27964-99-4
• MDL Number: MFCD00131934
• PubChem SID: 24898137; 24898143; 24898091; 24898763; 24898884; 24898835; 24898848; 24898164; 24898537; 162226726; 24898764
• PubChem CID: 16219815

CALCULATED PROPERTIES

• Acid pKa: 2.7382863
• H Acceptors: 4
• H Donor: 3
• LogD (pH = 5.5): -5.9555907
• LogD (pH = 7.4): -4.978252
• Log P: -3.2145348
• Molar Refractivity: 37.8095 cm^3
• Polarizability: 15.365045 Å^3
• Polar Surface Area: 89.34 Å^2
• Rotatable Bonds: 5
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Apperance: lyophilized powder

Safety Information

• German water hazard class: 3
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C

Product Information

• Suitability: suitable for cell culture
• Sterility: γ-irradiated
• Quality Level: PREMIUM
• Mol. Weight: average mol wt 30,000-70,000; average Mv >70,000; average Mv 1,000-4,000; mol wt >300,000; mol wt ≥300,000; mol wt 1,000-5,000; mol wt 15,000-30,000; mol wt 150,000-300,000; mol wt 30,000-70,000; mol wt 4,000-15,000; mol wt 70,000-150,000
• Linear Formula: D-Lys-(D-Lys)/n-D-Lys · xHBr; D-Lys-(D-Lys)n-D-Lys · xHBr

DETAILS

Sigma Aldrich - P6407

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Analysis Note
Molecular weight based on viscosity.
Application
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
This product has a higher binding site density, but is more viscous than P7280. It is a poly-D-lysine that can be used with cells that digest poly-L-lysine polymers.
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
General description
Poly-lysine polymers are useful molecules to prepare surfaces for cell attachment. Poly-lysine polymers are available in L and D conformations. Poly-L-lysine polymers can be digested by some cell types, whereas poly-D-lysines are stable. Poly-lysine polymers from 70 to 300 kDa provide sufficient attachment site density for good cell adherence. However, higher molecular weight poly-lysine polymers are more viscous and difficult to work with.The choice of poly-lysine polymer for a specific cell type and application should account for the susceptibility of the polymer to digestion, the required attachment site density and the difficulty in handling.

Sigma Aldrich - P4408

Analysis Note
Molecular weight based on viscosity.
Application
Poly-lysine with mol. wt. >30,000 is useful in promoting cell adhesion to solid substrates.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Sigma Aldrich - P7405

Analysis Note
分子量基于粘度。
Application
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。

Sigma Aldrich - P7280

Analysis Note
分子量基于粘度。
Application
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
This product has a lowerer binding site density, but is less viscous than P6407. It is a poly-D-lysine that can be used with cells that digest poly-L-lysine polymers.
有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。
General description
Poly-lysine polymers are useful molecules to prepare surfaces for cell attachment. Poly-lysine polymers are available in L and D conformations. Poly-L-lysine polymers can be digested by some cell types, whereas poly-D-lysines are stable. Poly-lysine polymers from 70 to 300 kDa provide sufficient attachment site density for good cell adherence. However, higher the molecular weight poly-lysine polymers are more viscous and difficult to work with.The choice of poly-lysine polymer for a specific cell type and application should account for the susceptibility of the polymer to digestion, the required attachment site density and the difficulty in handling.

Sigma Aldrich - P1149

Analysis Note
Molecular weight based on viscosity.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Sigma Aldrich - P7886

Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Sigma Aldrich - P6403

Analysis Note
Molecular weight based on viscosity.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Sigma Aldrich - P1024

Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Sigma Aldrich - P0899

Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Sigma Aldrich - P0296

Analysis Note
Molecular weight based on viscosity. Also assayed by MALLS.
Application
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Biochem/physiol Actions
Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells.

Sigma Aldrich - 81358

Application
Poly-lysine with mol. wt. >30,000 is useful in promoting cell adhesion to solid substrates.
Other Notes
Useful for promoting cell adhesion to solid substances1
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.