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Poly-D-lysine hydrobromide

Catalog No. P7280 Name Sigma Aldrich
CAS Number 27964-99-4 Website http://www.sigmaaldrich.com
M. F. C6H15BrN2O2 Telephone 1-800-521-8956
M. W. 227.0995 Fax
Purity Email
Storage Chembase ID: 132449


多聚-D-赖氨酸 氢溴酸盐
IUPAC name
2,6-diaminohexanoic acid hydrobromide
IUPAC Traditional name
lysine hydrobromide


CAS Number 27964-99-4
MDL Number MFCD00131934
PubChem SID 24898835


Mol. Weight average mol wt 30,000-70,000
Sterility γ-irradiated
Suitability suitable for cell culture
Apperance lyophilized powder
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3


Description (简体中文)
Analysis Note
Recommended as a cell culture substratum when using 0.5 - 1.0 mL of a 0.1 mg/ml solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application.
分子量 >30,000 的聚赖氨酸适用于促进细胞粘附到固体基质。
Other Notes
This product has a lowerer binding site density, but is less viscous than P6407. It is a poly-D-lysine that can be used with cells that digest poly-L-lysine polymers.
有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源。
General description
Poly-lysine polymers are useful molecules to prepare surfaces for cell attachment. Poly-lysine polymers are available in L and D conformations. Poly-L-lysine polymers can be digested by some cell types, whereas poly-D-lysines are stable. Poly-lysine polymers from 70 to 300 kDa provide sufficient attachment site density for good cell adherence. However, higher the molecular weight poly-lysine polymers are more viscous and difficult to work with.The choice of poly-lysine polymer for a specific cell type and application should account for the susceptibility of the polymer to digestion, the required attachment site density and the difficulty in handling.