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Genistein

Catalog No. S1342 Name Selleck Chemicals
CAS Number 446-72-0 Website http://www.selleckchem.com
M. F. C15H10O5 Telephone (877) 796-6397
M. W. 270.2369 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 1421

SYNONYMS

IUPAC name
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
IUPAC Traditional name
genistein

DATABASE IDS

CAS Number 446-72-0

PROPERTIES

Target EGFR EGFR
Salt Data Free Base
Solubility DMSO
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Prostate cancer
Biological Activity:
Genistein is a soy-derived isoflavone and phytoestrogen with antineoplastic activity. Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities. [1]

REFERENCES

  • http://www.cancer.gov/drugdictionary/?CdrID=43214