Cisplatin

• Catalog No.: S1166
• CAS Number: 15663-27-1
• M. F.: Cl2H4N2Pt
• M. W.: 298.02916
• Storage: -20°C

SYNONYMS

• IUPAC name: dichloroplatinumdiamine
• IUPAC Traditional name: diamminedichloroplatinum

DATABASE IDS

• CAS Number: 15663-27-1

PROPERTIES

• Salt Data: Free Base
• Solubility: DMSO
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: cancer
Biological Activity:
Cisplatin is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, small cell lung cancer, ovarian cancer, lymphomas, and germ cell tumors. It was the first member of a class of anti-cancer drugs which now also includes carboplatin and oxaliplatin. These platinum complexes react in vivo, binding to and causing crosslinking of DNA which ultimately triggers apoptosis . [1] 

REFERENCES

• Rebillard A et al. Curr Med Chem. 2008;15(26):2656-63