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Potassium Iodide

Catalog No. DB06715 Name DrugBank
CAS Number 7681-11-0 Website http://www.ualberta.ca/
M. F. IK Telephone (780) 492-3111
M. W. 166.00277 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 4452

SYNONYMS

IUPAC name
potassium iodide
IUPAC Traditional name
potassium ion iodide
Brand Name
ThyroShield

DATABASE IDS

CAS Number 7681-11-0
PubChem CID 4875
PubChem SID 99443267

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.
Indication Potassium Iodide is oral antithyroid agent. Potassium Iodide is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution.
Pharmacology It works in the thyroid gland. By inhibiting thyroid hormone synthesis and release, thyroid gland vascularity is reduced, thyroid gland tissue becomes firmer, thyroid cell size is reduced, follicular colloid reaccumulates, and bound iodine levels increase. As a protectant following radiation exposure, KI blocks the uptake of radioactive iodine isotopes by the thyroid gland thereby minimizing the risk of radiation-induced thyroid neoplasms.
External Links
Wikipedia

REFERENCES