potassium iodide

• ChemBase ID: 4452
• Molecular Formular: IK
• Molecular Mass: 166.00277
• Monoisotopic Mass: 165.86817968
• SMILES: [K+].[I-]
• Canonical SMILES: [K+].[I-]
• InChI: InChI=1S/HI.K/h1H;/q;+1/p-1
• InChIKey: NLKNQRATVPKPDG-UHFFFAOYSA-M

NAMES AND DATABASE IDS

Names

• IUPAC name: potassium iodide
• IUPAC Traditional name: potassium ion iodide; potassium iodide
• Brand Name: ThyroShield
• Synonyms: Potassium iodide, ultra dry; Potassium iodide, Puratronic®; Potassium Iodide; Potassium iodide solution; Kalii iodidum; Potassium iodide; POTASSIUM IODIDE, ACS; Potassium iodide solution; Potassium iodide concentrate; Potassium iodide, ACS; 碘化钾, 超干; 碘化钾, Puratronic®; 碘化钾 溶液; 碘化钾; 碘化钾; 碘化钾, ACS

Database IDs

• CAS Number: 7681-11-0
• EC Number: 213-659-4; 231-791-2; 231-659-4
• MDL Number: MFCD00011405
• Merck Index: 147643
• PubChem SID: 24845426; 24858301; 24852483; 24898914; 24853302; 24881869; 24852091; 99443267; 24866859; 24898376; 24861659; 24881868; 24863788; 24860730; 24861761; 160967884
• PubChem CID: 4875
• CHEBI ID: 8346
• ATC CODE: V03AB21; S01XA04; R05CA02
• CHEMBL: 1141
• Chemspider ID: 4709
• DrugBank ID: DB06715
• KEGG ID: D01016
• Unique Ingredient Identifier: 1C4QK22F9J
• Wikipedia Title: Potassium_iodide

CALCULATED PROPERTIES

• Acid pKa: 3.09
• H Acceptors: 0
• H Donor: 0
• LogD (pH = 5.5): 0.2
• LogD (pH = 7.4): 0.2
• Log P: 0.2
• Molar Refractivity: 0.0 cm^3
• Polarizability: 2.6527095 Å^3
• Polar Surface Area: 0.0 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: 128 g/100 ml (0 °C) ; 140 g/100 mL (20 °C) ; 176 g/100 mL (60°C) ; 206 g/100 mL (100°C) in water; 2 g/100 mL (ethanol) ; soluble in acetone (1.31 g/100 mL) ; slightly soluble in ether, ammonia; H2O: soluble1 M at 20 °C, clear, colorless; Soluble in water, alcohol, acetone, and glycerol
• Apperance: -10 Mesh Beads, Ampouled under argon; beads; Crystalline; crystals and lumps; Granular; Powder; white crystalline solid
• Melting Point: 681 °C(lit.); 681°C; 681°C
• Boiling Point: 1330°C; 1330°C
• Density: 3.12; 3.123 g/cm^3
• Refractive Index: 1.677
• Vapor Pressure: 1 mmHg ( 745 °C)
• pH: 6.0-9.0 (20 °C, 5%); 6.0-9.0 (25 °C, 1 M in H2O); 6.0-9.2 (25 °C, 5%); 6.0-9.2 (25 °C, 50 mg/mL in H2O)

Safety Information

• Storage Condition: -20°C; Room Temperature (15-30°C), Desiccate, Protect from light
• Storage Warning: Hygroscopic
• RTECS: TT2975000
• European Hazard Symbols: Corrosive (C); Harmful (Xn)
• German water hazard class: 1; nwg
• Risk Statements: 22-34; 22-36/38; R:22
• Safety Statements: 26; 26-36/37/39-45; S:36/37/39
• TSCA Listed: 是
• EU Index: Not listed
• GHS Pictograms: GHS05; GHS07
• GHS Signal Word: Danger; Warning
• NFPA704:
  

  0

  1

  0
• GHS Hazard statements: H302-H315-H319; H314
• GHS Precautionary statements: P280-P305 + P351 + P338-P310; P305 + P351 + P338
• Personal Protective Equipment: Eyeshields, Gloves; Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US); Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Product Information

• Purity: ≥99.0%; ≥99.0% (AT); ≥99.5%; ≥99.5% (AT); ≥99.99% trace metals basis; ≥99.999% (metals basis); 98%; 99%; 99.0% min; 99.0-100.5% (calc. to the dried substance); 99.9% (metals basis); 99.99% (metals basis); 99.995% (metals basis); 99.998% (metals basis); 99.998% trace metals basis
• Concentration: 0.1 M; 0.1 M KI; 1 M KI; 15 % (w/v); 3 M KI
• Grade: ACS; ACS reagent; anhydrous; JIS special grade; Ph Eur; puriss.; puriss. p.a.; purum p.a.; REAGENT; ReagentPlus®; SAJ first grade; TraceSELECT®
• Salt Data: inorganic salt
• Particle Size: -10 mesh
• Packaging: pkg of 0.1 mol (16.601 g KI)
• Suitability: complies for appearance of solution; meets EP, BP, USP testing specifications; meets USP testing specifications; plant cell culture tested; suitable for oxidant determination
• Impurities: <100 ppm water; ≤0.0005% heavy metals (as Pb); ≤0.0005% P; ≤0.001% heavy metals (as Pb); ≤0.001% N compounds; ≤0.001% total nitrogen (N); ≤0.005% Insoluble matter; ≤0.005% insolubles; ≤0.005% thiosulfate (S2O3); ≤0.01% thiosulfate (S2O3); ≤0.02% free alkali (as KOH); ≤10 mg/kg total nitrogen; ammonium, in accordance; insoluble matter, passes filter test; organic volatile impurities, complies (GC); residual solvents, in accordance
• Cation Traces: Al: ≤0.0005%; Al: ≤0.02 mg/kg; Al: ≤5 mg/kg; As: ≤0.01 mg/kg; As: ≤0.1 mg/kg; Ba: ≤0.002%; Ba: ≤0.5 mg/kg; Ba: ≤10 mg/kg; Ba: ≤20 mg/kg; Ba: ≤5 mg/kg; Ba:, in accordance; Bi: ≤5 mg/kg; Ca: ≤0.001%; Ca: ≤0.002%; Ca: ≤0.1 mg/kg; Ca: ≤10 mg/kg; Ca: ≤50 mg/kg; Cd: ≤0.01 mg/kg; Cd: ≤5 mg/kg; Cd: ≤50 mg/kg; Ce: ≤0.01 mg/kg; Co: ≤0.01 mg/kg; Co: ≤5 mg/kg; Co: ≤50 mg/kg; Cr: ≤0.01 mg/kg; Cr: ≤5 mg/kg; Cu: ≤0.0005%; Cu: ≤0.01 mg/kg; Cu: ≤5 mg/kg; Cu: ≤50 mg/kg; Eu: ≤0.01 mg/kg; Fe: ≤0.0005%; Fe: ≤0.05 mg/kg; Fe: ≤10 mg/kg; Fe: ≤2 mg/kg; Fe: ≤3 mg/kg; Fe: ≤3 ppm; Fe: ≤5 mg/kg; Fe: ≤50 mg/kg; heavy metals (as Pb): ≤5 ppm; Hg: ≤0.005 mg/kg; La: ≤0.01 mg/kg; Li: ≤0.5 mg/kg; Li: ≤5 mg/kg; Mg: ≤0.0005%; Mg: ≤0.001%; Mg: ≤0.05 mg/kg; Mg: ≤10 mg/kg; Mg: ≤5 mg/kg; Mn: ≤0.01 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤0.005%; Na: ≤0.05%; Na: ≤2000 mg/kg; Na: ≤300 mg/kg; Na: ≤5 mg/kg; Na: ≤50 mg/kg; NH4+: ≤0.05%; Ni: ≤0.01 mg/kg; Ni: ≤5 mg/kg; Ni: ≤50 mg/kg; Pb: ≤0.001%; Pb: ≤0.01 mg/kg; Pb: ≤5 mg/kg; Pb: ≤50 mg/kg; Sc: ≤0.01 mg/kg; Sm: ≤0.01 mg/kg; Sr: ≤0.1 mg/kg; Sr: ≤5 mg/kg; Tl: ≤0.01 mg/kg; Y: ≤0.01 mg/kg; Yb: ≤0.01 mg/kg; Zn: ≤0.0005%; Zn: ≤0.01 mg/kg; Zn: ≤5 mg/kg; Zn: ≤50 mg/kg
• Antion Traces: bromide, chloride (as Cl-): ≤100 mg/kg; bromide, chloride (as Cl-): ≤200 mg/kg; bromide, chloride (as Cl-): ≤50 mg/kg; chloride (Cl-): ≤0.01%; chloride, bromide (as Cl)-: ≤0.01%; iodate (IO3-): ≤2 mg/kg; iodate (IO3-): ≤3 mg/kg; iodate (IO3-): ≤3 ppm; iodate (IO3-): in accordance; nitrate (NO3-): in accordance; nitrite (NO2-): in accordance; phosphate (PO43-): ≤0.001%; phosphate (PO43-): ≤10 mg/kg; sulfate (SO42-): ≤0.005%; sulfate (SO42-): ≤10 mg/kg; sulfate (SO42-): ≤100 mg/kg; sulfate (SO42-): ≤50 mg/kg
• Shelf Life: (limited shelf life, expiry date on the label)
• Loss on Drying: ≤0.2% loss on drying; ≤0.2% loss on drying, 105 °C; ≤0.2% loss on drying, 150 °C; ≤0.5% loss on drying, 105 °C; ≤0.5% loss on drying, 110 °C
• Quality: meets analytical specification of Ph. Eur. BP, USP; volumetric
• Factor: 1.000 ±0.001; 1.000 ±0.005
• Pharmacopeia: testing & handling conforms to Pharmacopeia
• Product Line: BioUltra
• abs.: absorption1M/273 nm, H2O cut-off
• Linear Formula: KI

DETAILS

DrugBank - DB06715

• Drug Groups: approved
• Description: Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.
• Indication: Potassium Iodide is oral antithyroid agent. Potassium Iodide is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution.
• Pharmacology: It works in the thyroid gland. By inhibiting thyroid hormone synthesis and release, thyroid gland vascularity is reduced, thyroid gland tissue becomes firmer, thyroid cell size is reduced, follicular colloid reaccumulates, and bound iodine levels increase. As a protectant following radiation exposure, KI blocks the uptake of radioactive iodine isotopes by the thyroid gland thereby minimizing the risk of radiation-induced thyroid neoplasms.
• External Links: Wikipedia

MP Biomedicals - 02191513

Crystalline

MP Biomedicals - 02152562

ACS Reagent Grade

Selleck Chemicals - S1897

Research Area: Endocrinology
Biological Activity:
Potassium iodide is used to treat overactive thyroid and to protect the thyroid gland from the effects of radiation from inhaled or swallowed radioactive iodine. It may be used before and after administration of medicine containing radioactive iodine or after accidental exposure to radioactive iodine. [1]

Sigma Aldrich - 60399

Other Notes
Chaotropic agent which, in high concentrations can dissolve a gel matrix1; Recovery of DNA from gel slices by gel dissolution2,3

Sigma Aldrich - 204102

Packaging
10, 50 g in amber poly
250 g in poly bottle

Sigma Aldrich - 429422

Packaging
5, 25 g in ampule

Sigma Aldrich - 35175

General description
Visit our Titration Center to learn more.
Packaging
The suffix -VP or -VOLPAC in the product number indicates packaging in 5 or 10 L VOLPAC containers.

Sigma Aldrich - 34275

General description
Visit our Titration Center to learn more.

Sigma Aldrich - 30533

Application
Speciation Analysis by Hydride Generation-AAS together with ascorbic acid
Legal Information
TraceSELECT is a registered trademark of Sigma-Aldrich Co. LLC

Sigma Aldrich - 38110

General description
Visit our Titration Center to learn more.
concentration after dilution to 1L: 0.1mol/L; amount of substance 0.1mol (16.601 g KI)

Sigma Aldrich - 207969

Packaging
100, 500 g in poly bottle
Legal Information
ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Sigma Aldrich - 221945

Packaging
12 kg in poly drum
2.5 kg in poly bottle
5, 100, 500 g in poly bottle
50 kg in fiber drum

REFERENCES

• http://www.rxlist.com/phospholine-drug.htm