Vildagliptin

• Catalog No.: Bio-0937
• CAS Number: 274901-16-5
• M. F.: C17H25N3O2
• M. W.: 303.3993

SYNONYMS

• IUPAC name: (2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile
• IUPAC Traditional name: (2S)-1-{2-[(3-hydroxyadamantan-1-yl)amino]acetyl}pyrrolidine-2-carbonitrile
• Synonyms: Zomelis; Galvus; LAF237

DATABASE IDS

• CAS Number: 274901-16-5

PROPERTIES

• Application(s): Anti-hyperglycemic agent
• Mechanism of Action: Dipeptidyl peptidase-4 (DPP-4) inhibitor

REFERENCES

• 1. Ahre'n, B; Landin-Olsson, M; Jansson, PA; Svensson, M; Holmes, D; Schweizer, A (2004). "Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels
• in type 2 diabetes". The Journal of clinical endocrinology and metabolism 89 (5): 2078?4.
• 2. Mentlein, R; Gallwitz, B; Schmidt, WE (1993). "Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible
• for their degradation in human serum". European journal of biochemistry / FEBS 214 (3): 829?5.