Retapamulin

• Catalog No.: Bio-0935
• CAS Number: 224452-66-8
• M. F.: C30H47NO4S
• M. W.: 517.76348

SYNONYMS

• IUPAC name: (1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxotricyclo[5.4.3.0^1,^8]tetradecan-6-yl 2-{[(1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]sulfanyl}acetate
• IUPAC Traditional name: (1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxotricyclo[5.4.3.0^1,^8]tetradecan-6-yl 2-{[(1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]sulfanyl}acetate
• Synonyms: Altabax; Altargo

DATABASE IDS

• CAS Number: 224452-66-8

PROPERTIES

• Application(s): Pleuromutilin antibiotic
• Mechanism of Action: Inhibit protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes

REFERENCES

• 1. Jones R, Fritsche T, Sader H, Ross J (2006). "Activity of retapamulin (SB-275833), a novel pleuromutilin, against selected resistant gram-positive cocci". Antimicrob Agents Chemother 50 (7): 2583?
• .
• 2. Physicans' Desk Reference(ISBN 1-56363-660-3) (62 ed.). 2007. pp. 1318?0.