Pergolide mesylate

• Catalog No.: Bio-0934
• CAS Number: 66104-22-1
• M. F.: C20H30N2O3S2
• M. W.: 410.5938

SYNONYMS

• IUPAC name: (2R,4R,7R)-4-[(methylsulfanyl)methyl]-6-propyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene; methanesulfonic acid
• IUPAC Traditional name: (2R,4R,7R)-4-[(methylsulfanyl)methyl]-6-propyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene; methanesulfonic acid
• Synonyms: Pergotoliderived; Permax; Pergolida; Pergolidum

DATABASE IDS

• CAS Number: 66104-22-1

PROPERTIES

• Application(s): Used to treat various conditions including Parkinson's disease, hyperprolactinemia, and restless leg syndrome.
• Application(s): Also used for veterinary purposes.
• Salt Data: Mesylate
• Mechanism of Action: Agonist at the dopamine D2, D1 and serotonin 5-HT(1A), 5-HT(1B), 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptors

REFERENCES

• Lemberger, L. et al., Science (Washington, D.C.), 1979
• Rubin, A. et al., Clin. Pharmacol. Ther. (St. Louis), 1981