Tianeptine sodium

• Catalog No.: Bio-0923
• CAS Number: 30123-17-2
• M. F.: C21H25N2NaO4S
• M. W.: 424.48897

SYNONYMS

• IUPAC name: sodium 7-({10-methyl-9,9-dioxo-9λ^6-thia-10-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}amino)heptanoate
• IUPAC Traditional name: sodium 7-({10-methyl-9,9-dioxo-9λ^6-thia-10-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}amino)heptanoate
• Synonyms: Coaxil; Stablon; Tatinol

DATABASE IDS

• CAS Number: 30123-17-2

PROPERTIES

• Application(s): Antidepressant
• Application(s): Anxiolytic
• Application(s): Neuroprotective
• Application(s): Analgesic
• Application(s): Anticonvulsant
• Application(s): Effective for asthma treatment
• Salt Data: Na+
• Mechanism of Action: Selective serotonin 5-HT reuptake enhancer

REFERENCES

• 1. Mennini T, Mocaer E, Garattini S. Tianeptine, a selective enhancer of serotonin uptake in rat brain. Naunyn Schmiedebergs Arch Pharmacol. 1987 Nov;336(5):478-82.
• 2. Kato G, Weitsch AF. Neurochemical profile of tianeptine, a new antidepressant drug. Clin Neuropharmacol. 1988;11 Suppl 2:S43-50.
• 3. Uzbay IT, Cinar MG, Aytemir M, Tuglular I. Analgesic effect of tianeptine in mice. Life Sci. 1999;64(15):1313-9.
• 4. Plaisant F, Dommergues MA, Spedding M, Cecchelli R, Brillault J, Kato G, Munoz C, Gressens P. Neuroprotective properties of tianeptine: interactions with cytokines.
• Neuropharmacology. 2003 May;44(6):801-9.
• 5. Lechin F, van der Dijs B, Orozco B, Jara H, Rada I, Lechin ME, Lechin AE.
• The serotonin uptake-enhancing drug tianeptine suppresses asthmatic symptoms in children: a double-blind, crossover, placebo-controlled study. J Clin Pharmacol. 1998 Oct;38(10):918-25.