Dobutamine hydrochloride

• Catalog No.: Bio-0922
• CAS Number: 52663-81-7
• M. F.: C18H23NO3
• M. W.: 301.38012

SYNONYMS

• IUPAC name: 4-(2-{[(2S)-4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
• IUPAC Traditional name: 4-(2-{[(2S)-4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
• Synonyms: Inofrex; Dobutrex

DATABASE IDS

• CAS Number: 52663-81-7

PROPERTIES

• Application(s): Sympathomimetic drug
• Application(s): Used in the treatment of heart failure and cardiogenic shock
• Mechanism of Action: Stimulation of beta1 receptors of the sympathetic nervous system

REFERENCES

• Tuttle RR, Mills J (January 1975). "Dobutamine: development of a new catecholamine to selectively increase cardiac contractility". Circ Res 36 (1): 185?6. PMID 234805.
• Rang HP, Dale MM, Ritter JM, Flower RJ. Rang and Dale's Pharmacology.
• Shen, Howard (2008). Illustrated Pharmacology Memory Cards: PharMnemonics. Minireview. p. 6. ISBN 1-59541-101-1.
• Parker K, Brunton L, Goodman LS, Blumenthal D, Buxton I (2008). Goodman & Gilman's manual of pharmacology and therapeutics. McGraw-Hill Medical. pp. 159. ISBN 0-07-144343-6.
• Tibayan FA, Chesnutt AN, Folkesson HG, Eandi J, Matthay MA (1997). "Dobutamine increases alveolar liquid clearance in ventilated rats by beta-2 receptor stimulation".
• Am. J. Respir. Crit. Care Med. 156 (2 Pt 1): 438?4. PMID 9279221