Tubeimoside A

• Catalog No.: Bio-0920
• CAS Number: 102040-03-9
• M. F.: C63H98O29
• M. W.: 1319.43482

SYNONYMS

• IUPAC name: (1S,4S,7S,8S,9R,11S,13S,14S,18S,22S,25S,27R,28S,29S,30R,32R,34R,35S,37R,38R,41R,42R,46S,53S,54R,55R,56R,57S,58R)-7,8,18,28,29,35,55,56,58-nonahydroxy-30,54-bis(hydroxymethyl)-13,18,37,41,48,48,53,54-octamethyl-57-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}-3,5,10,12,15,21,24,26,31,33-decaoxadecacyclo[39.9.3.2^1^1,^1^4.2^2^2,^2^5.1^3^4,^3^8.0^1,^4^6.0^4,^9.0^2^7,^3^2.0^3^7,^4^2.0^4^5,^5^3]octapentacont-44-ene-2,16,20-trione
• IUPAC Traditional name: (1S,4S,7S,8S,9R,11S,13S,14S,18S,22S,25S,27R,28S,29S,30R,32R,34R,35S,37R,38R,41R,42R,46S,53S,54R,55R,56R,57S,58R)-7,8,18,28,29,35,55,56,58-nonahydroxy-30,54-bis(hydroxymethyl)-13,18,37,41,48,48,53,54-octamethyl-57-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}-3,5,10,12,15,21,24,26,31,33-decaoxadecacyclo[39.9.3.2^1^1,^1^4.2^2^2,^2^5.1^3^4,^3^8.0^1,^4^6.0^4,^9.0^2^7,^3^2.0^3^7,^4^2.0^4^5,^5^3]octapentacont-44-ene-2,16,20-trione
• Synonyms: Tubeimoside 1

DATABASE IDS

• CAS Number: 102040-03-9

PROPERTIES

• Application(s): Antitumour activity
• Application(s): Anti-inflammatory activity
• Biological Source: Constit. of Bolbostemma paniculatum
• Mechanism of Action: DNA synthesis inhibitor
• Mechanism of Action: Apoptosis inducer

REFERENCES

• 1. Yu L, Ma R, Wang Y, Nishino H. Potent anti-tumor activity and low toxicity of tubeimoside 1 isolated from Bolbostemma paniculatum. Planta Med. 1994 Jun;60(3):204-8.
• 2. Yu TX, Ma RD, Yu LJ. Structure-activity relationship of tubeimosides in anti-inflammatory, antitumor, and antitumor-promoting effects. Acta Pharmacol Sin. 2001 May;22(5):463-8.
• 3. Weng XY, Ma RD, Yu LJ. [Apoptosis of human nasopharyngeal carcinoma CNE-2Z cells induced by tubeimoside I] Ai Zheng. 2003 Aug;22(8):806-11. [Article in Chinese]