Neohesperidin dihydrochalcone

• Catalog No.: Bio-0910
• CAS Number: 20702-77-6
• M. F.: C28H40O17
• M. W.: 648.607

SYNONYMS

• IUPAC name: 1-(4-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,6-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)propan-1-one dihydrate
• IUPAC Traditional name: 1-(4-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,6-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)propan-1-one dihydrate
• Synonyms: Hesperetin 7-neohesperidoside

DATABASE IDS

• CAS Number: 20702-77-6

PROPERTIES

• Application(s): Artificial sweetener
• Application(s): Flavour enhancer
• Application(s): Antioxidant
• Biological Source: Derived semisynthetically from 3',5,7-Trihydroxy-4'-methoxyflavanone
• Salt Data: 2 H2O
• Mechanism of Action: Activates the human sweet receptor TAS1R2+TAS1R3
• Mechanism of Action: Radical scavenger

REFERENCES

• 1. Winnig M, Bufe B, Kratochwil NA, Slack JP, Meyerhof W. The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor. BMC Struct Biol. 2007 Oct 12;7:66.
• 2. Choi JM, Yoon BS, Lee SK, Hwang JK, Ryang R.
• Antioxidant properties of neohesperidin dihydrochalcone: inhibition of hypochlorous acid-induced DNA strand breakage, protein degradation, and cell death. Biol Pharm Bull. 2007 Feb;30(2):324-30.