Metergoline

• Catalog No.: Bio-0869
• CAS Number: 17692-51-2
• M. F.: C25H29N3O2
• M. W.: 403.51666

SYNONYMS

• IUPAC name: benzyl N-{[(2R,4S,7R)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraen-4-yl]methyl}carbamate
• IUPAC Traditional name: benzyl N-{[(2R,4S,7R)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraen-4-yl]methyl}carbamate
• Synonyms: Methergoline; Liserdol; Al-Migren

DATABASE IDS

• CAS Number: 17692-51-2

PROPERTIES

• Application(s): Analgesic
• Application(s): Antipyretic
• Application(s): Migraine disorgers therapy
• Mechanism of Action: Dopamine agonist
• Mechanism of Action: Serotonin receptor antagonist
• Mechanism of Action: 5-HT2 antagonist
• Mechanism of Action: 5-HT1 antagonist and 5-HT1D ligand
• Mechanism of Action: Has moderate affinity for 5-HT6 and high affinity for 5-HT7

REFERENCES

• Bagdy et al (1992) Pharmacological characterization of serotonin receptor subtypes involved in vasopressin and plasma renin activity responses to serotonin agonists. Eur.J.Pharmacol. 210 285.