Trioxysalen

• Catalog No.: Bio-0865
• CAS Number: 3902-71-4
• M. F.: C14H12O3
• M. W.: 228.24328

SYNONYMS

• IUPAC name: 2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one
• IUPAC Traditional name: 2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one
• Synonyms: Dermetrix; trisoralen; trimethylpsoralen; Levrison; Tripsos; 4,5',8-Trimethylpsoralen

DATABASE IDS

• CAS Number: 3902-71-4

PROPERTIES

• Application(s): Medicinal pigmentation agent
• Application(s): Tool used in molecular biology for labelling and isolating nascent DNA fragments
• Application(s): Dermatological agent
• Biological Source: Phytotoxic metab. of pink rot disease, produced by Sclerotinia sclerotiorum
• Application(s): Photosensitiser
• Application(s): Radiosensitizer
• Mechanism of Action: Action depends on the presence of functional melanocytes and their proliferation by photoactivated drug
• Mechanism of Action: Conjugates and forms covalent-bonds with DNA which leads to the formation of both monofunctional and bifunctional adducts upon photoactivation
• Mechanism of Action: Exact mechanism with epidermal melanocytes and keratinocytes unknown.

REFERENCES

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