Isoguanosine

• Catalog No.: Bio-0849
• CAS Number: 1818-71-9
• M. F.: C10H13N5O5
• M. W.: 283.24072

SYNONYMS

• IUPAC name: 6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,9-dihydro-2H-purin-2-one
• IUPAC Traditional name: 6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,9-dihydro-2H-purin-2-one
• Synonyms: 9-beta- D -Ribofuranosylisoguanine; Crotonoside; 6-Amino-9-beta- D -ribofuranosyl-9 H -purin-2(1 H )-one; 2-Hydroxyadenosine

DATABASE IDS

• CAS Number: 1818-71-9

PROPERTIES

• Application(s): Regulates brain disorders,
• Application(s): Antioxidant
• Biological Source: Occurs in the seeds of Croton tiglium . Also isol. from the nudibranch Diaulula sandiegensis
• Description: Tautomers
• Mechanism of Action: Stimulates cyclic AMP incorporation into brain tissue
• Mechanism of Action: Inosine monophosphate pyrophosphonylase inhibitor
• Mechanism of Action: Glutamic acid dehydrogenase inhibitor
• Mechanism of Action: Antioxidant

REFERENCES

• Cherbuliez, E. et al., Helv. Chim. Acta, 1932, 15, 464; 978, (isol)
• Spies, J.R., J.A.C.S., 1939, 61, 350, (occur)
• Davoll, J., J.A.C.S., 1951, 73, 3174, (synth, isol)
• Yamazaki, A. et al., Chem. Pharm. Bull., 1968, 16, 2172, (synth)
• Miura, K. et al., Chem. Pharm. Bull., 1975, 23, 2064, (synth)
• Sepiol, J. et al., Z. Naturforsch., C, 1976, 37, 361, (uv)
• Fuhrmann, F.A. et al., Science (Washington, D.C.), 1981, 212, 557, (isol)
• Nair, V. et al., J.O.C., 1985, 50, 406, (synth, pmr)
• Divakar, K.J. et al., J.C.S. Perkin 1, 1991, 771, (synth, uv, pmr, cmr)
• Chern, J.-W. et al., J.O.C., 1991, 56, 4213, (synth)
• De Napoli, L. et al., J.C.S. Perkin 1, 1995, 15, (synth, bibl)