Amantadine

• Catalog No.: Bio-0821
• CAS Number: 768-94-5
• M. F.: C10H17N
• M. W.: 151.24868

SYNONYMS

• IUPAC name: adamantan-1-amine
• IUPAC Traditional name: adamantan-1-amine

DATABASE IDS

• CAS Number: 768-94-5

PROPERTIES

• Application(s): Antiviral agent
• Application(s): prophylactic drug for influenza
• Application(s): Also has antiparkinsonian props.
• Mechanism of Action: Dopaminergic
• Mechanism of Action: Postulated antiparkinsonian mechanism: causes dopamine release from dopaminergic terminals that may remain in the substantia-nigra of parkinsonian patients
• Mechanism of Action: May cause dopamine release from central sites other than the substantia-nigra
• Mechanism of Action: Exact virucidal mechanism not completely understood
• Mechanism of Action: Apparent virucidal mechanism: influenza type-A specific; influenza type-A viral nucleic-acid into host-cell
• Mechanism of Action: May interfere with viral penetration into cells.

REFERENCES

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• Aldrich Library of 13C and 1H FT NMR Spectra , 1992, 1 , 1229C, (nmr)
• Aldrich Library of FT-IR Spectra: Vapor Phase , 1989, 3 , 409D, (ir)
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• Lewis, R.J. , Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AED250; TJG250