Azaperone

• Catalog No.: Bio-0808
• CAS Number: 1649-18-9
• M. F.: C19H22FN3O
• M. W.: 327.3958832

SYNONYMS

• IUPAC name: 1-(4-fluorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]butan-1-one
• IUPAC Traditional name: 1-(4-fluorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]butan-1-one
• Synonyms: Fluoperidol; Stresnil

DATABASE IDS

• CAS Number: 1649-18-9

PROPERTIES

• Application(s): Psychosedative
• Application(s): Neuroleptic
• Application(s): Sedative
• Application(s): Vet. tranquilliser
• Mechanism of Action: 5-HT receptor antagonist
• Mechanism of Action: Dopamine antagonist

REFERENCES

• U.S. Pat., 1960, Janssen, 2 958 694; CA, 55, 9439d, (synth)
• Frigerio, A. et al., Org. Mass Spectrom., 1972, 6, 1051, (ms)
• Niemegeers, C.J.E. et al., Arzneim.-Forsch., 1974, 24, 1798, (pharmacol, tox)
• Serrano, L. et al., Res. Vet. Sci., 1976, 20, 316, (pharmacol)
• Koch, M.H.J. et al., Acta Cryst. B, 1977, 33, 1975, (cryst struct)
• Azibi, M. et al., Pharm. Acta Helv., 1981, 56, 190, (polymorphism)
• Van Boven, M. et al., J. Anal. Toxicol., 1992, 16, 33, (metab, chromatogr)
• Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 679
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 9th edn., Van Nostrand Reinhold, 1996, FLU000