Pirenzepine

• Catalog No.: Bio-0807
• CAS Number: 28797-61-7
• M. F.: C19H21N5O2
• M. W.: 351.40234

SYNONYMS

• IUPAC name: 2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
• IUPAC Traditional name: 2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
• Synonyms: Gastrozepin

DATABASE IDS

• CAS Number: 28797-61-7

PROPERTIES

• Application(s): Antiemetic
• Application(s): Spasmolytic
• Application(s): Used for gastric ulcer treatment
• Mechanism of Action: Muscarine M 1 receptor antagonist
• Mechanism of Action: Spasmolytic
• Mechanism of Action: Parasympatholytic

REFERENCES

• South African Pat., 1970, 69 05 933; CA, 73, 77292m, (synth, pharmacol)
• Eberlein, W. et al., Arzneim.-Forsch., 1977, 27, 356; 684, (pharmacol)
• Ruzic-Toros, Z. et al., Acta Cryst. C, 1983, 39, 93, (cryst struct)
• Kovac, T. et al., J. Het. Chem., 1983, 20, 1339, (synth)
• Feng, J. et al., CA, 1984, 101, 110880, (synth)
• Bechtel, W.D. et al., Arzneim.-Forsch., 1986, 36, 793, (pharmacol)
• El-Obeid, H.A. et al., Anal. Profiles Drug Subst., 1987, 16, 445, (rev, synth, anal, pharmacol)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 5258
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 430
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, GCE500