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Isoxicam

Catalog No. Bio-0802 Name InterBioScreen
CAS Number 34552-84-6 Website http://www.ibscreen.com
M. F. C14H13N3O5S Telephone +7 49652 40091
M. W. 335.33512 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 157732

SYNONYMS

IUPAC name
4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-2H-1λ6,2-benzothiazine-3-carboxamide
IUPAC Traditional name
4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-1,1-dioxo-2H-1λ6,2-benzothiazine-3-carboxamide

DATABASE IDS

CAS Number 34552-84-6

PROPERTIES

Application(s) Antiinflammatory
Application(s) Antipyretic agent
Application(s) Analgesic
Mechanism of Action Prostaglandin antagonist

DETAILS

REFERENCES

  • DiPasquale, G. et al., Agents Actions, 1975, 5, 256, (pharmacol)
  • Zinnes, H. et al., J. Med. Chem., 1982, 25, 12, (synth, pharmacol)
  • Yakatan, G.J., Semin. Arthritis Rheum., 1982, 12, 153, (rev)
  • DiPasquale, G., Drugs of Today (Barcelona), 1983, 19, 119, (rev)
  • Borondy, P.E. et al., Drug Metab. Dispos., 1984, 12, 444, (metab)
  • Svoboda, J. et al., Coll. Czech. Chem. Comm., 1986, 51, 1133, (synth)
  • Dalla Croce, P. et al., J. Chem. Res., Synop., 1986, 150, (synth)
  • Woolf, T.F. et al., Drug Metab. Dispos., 1989, 17, 662, (metab, exp)
  • Woolf, T.F. et al., Eur. J. Drug Metab. Pharmacokinet., 1992, 17, 21, (metab, human)
  • Tsai, R. et al., Helv. Chim. Acta, 1993, 76, 842, (pKa, props)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 21