Valsartan

• Catalog No.: Bio-0796
• CAS Number: 137862-53-4
• M. F.: C24H29N5O3
• M. W.: 435.51876

SYNONYMS

• IUPAC name: (2S)-3-methyl-2-[N-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid
• IUPAC Traditional name: (2S)-3-methyl-2-[N-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid
• Synonyms: Valtan

DATABASE IDS

• CAS Number: 137862-53-4

PROPERTIES

• Application(s): Antihypertensive agent
• Mechanism of Action: Angiotensin 2 receptor antagonist

REFERENCES

• Eur. Pat., 1991, Ciba-Geigy, 443 983; CA, 116, 151772t, (synth, pharmacol)
• Criscione, L. et al., Br. J. Pharmacol., 1993, 110, 761, (pharmacol)
• Wood, J.M. et al., Hypertension (Dallas), 1993, 21, 1056, (pharmacol)
• Buhlmayer, P. et al., Bioorg. Med. Chem. Lett., 1994, 4, 29, (synth)
• Markham, A. et al., Drugs, 1997, 54, 299-311, (rev)
• Langley, H.D. et al., Drugs, 1999, 57, 751-755, (rev)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 960