Amrinone

• Catalog No.: Bio-0795
• CAS Number: 60719-84-8
• M. F.: C10H9N3O
• M. W.: 187.19796

SYNONYMS

• IUPAC name: 3-amino-5-(pyridin-4-yl)-1,2-dihydropyridin-2-one
• IUPAC Traditional name: 3-amino-5-(pyridin-4-yl)-1,2-dihydropyridin-2-one
• Synonyms: Inamrinone; Inocor

DATABASE IDS

• CAS Number: 60719-84-8

PROPERTIES

• Application(s): Cardiac inotropic agent
• Mechanism of Action: Phosphodiesterase inhibitor
• Mechanism of Action: cAMP agonist

REFERENCES

• U.S. Pat., 1978, 4 107 315; CA, 90, 103844r, (synth)
• Alousi, A.A. et al., Pharmacol. Biochem. Prop. Drug Subst., 1981, 3, 120, (rev, pharmacol)
• Ward, A. et al., Drugs, 1983, 26, 468, (rev, pharmacol)
• Gomez-Parra, V. et al., Arch. Pharm. (Weinheim, Ger.), 1984, 317, 183, (synth)
• Perry, R.S., Drugs of Today (Barcelona), 1984, 20, 381, (rev)
• Robertson, D.W. et al., J. Med. Chem., 1986, 29, 635, (cryst struct)
• Niedrich, H. et al., Pharmazie, 1986, 41, 173; 176; 181, (synth, cryst struct, tautom)
• Landmann, H. et al., Arch. Toxicol., Suppl., 1988, 418, (tox, rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 663
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AOD375