Lidocaine

• Catalog No.: Bio-0767
• CAS Number: 137-58-6
• M. F.: C14H22N2O
• M. W.: 234.33728

SYNONYMS

• IUPAC name: 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
• IUPAC Traditional name: 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
• Synonyms: Xylocaine; Xilina; Xyline; Xycaine; Broncaine

DATABASE IDS

• CAS Number: 137-58-6

PROPERTIES

• Application(s): Local anaesthetic
• Application(s): Antiarrhythmic agent
• Mechanism of Action: Potassium channel (K ATP and K Vol ) blocker

REFERENCES

• Harms, A.F. et al., J. Med. Chem., 1961, 4, 575, (synth, pharmacol)
• Garland, W.A. et al., Biomed. Mass Spectrom., 1974, 1, 124, (ms)
• Jones, R.L., J. Pharm. Sci., 1974, 63, 1170, (ir)
• Yoo, C.S. et al., Acta Cryst. B, 1975, 31, 1354, (cryst struct)
• Singh, S.P. et al., Spectrosc. Lett., 1979, 12, 95, (pmr)
• Noneman, J.W. et al., Drug Treat. Card. Arrhythmias, 1983, 193, (rev, pharmacol)
• Groeningsson, K. et al., Anal. Profiles Drug Subst., 1985, 14, 207, (rev)
• Powell, M.F., Anal. Profiles Drug Subst., 1986, 15, 761, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 3325, (synonyms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1010
• Comer, A.M. et al., Drugs, 2000, 59, 245-249, (rev)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, DHK400; DHK600