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Sulfafurazole

Catalog No. Bio-0765 Name InterBioScreen
CAS Number 127-69-5 Website http://www.ibscreen.com
M. F. C11H13N3O3S Telephone +7 49652 40091
M. W. 267.30422 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 148

SYNONYMS

IUPAC name
4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
IUPAC Traditional name
4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
Synonyms
Neoxazol
Soxomide
Sulfisoxazole
Thiasin
Amidoxal
Gantrisin

DATABASE IDS

CAS Number 127-69-5

PROPERTIES

Application(s) Antiseptic
Application(s) Protozoacide
Application(s) Short-acting sulfonamide used for urinary tract infections.
Application(s) Low acute toxicity
Mechanism of Action Folate antagonist
Mechanism of Action Restrict folate synthesis through competitive antagonism of PABA

DETAILS

REFERENCES

  • Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 101A, (nmr)
  • Hoeprich, P.D., Antimicrob. Agents Chemother., 1967, 697, (pharmacol)
  • Rudy, B.C. et al., Anal. Profiles Drug Subst., 1973, 2, 487, (rev, synth)
  • Manzo, R.H. et al., J. Pharm. Sci., 1973, 62, 152, (uv)
  • IARC Monog., 1980, 24, 275; Suppl. 7, 347; Suppl. 6, 502, (rev, tox)
  • Chatterjee, C. et al., Acta Cryst. B, 1982, 38, 1845, (cryst struct)
  • Bult, A., Pharm. Weekbl., Sci. Ed., 1983, 5, 77, (cmr, tautom)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1971
  • Kirk-Othmer Encycl. Chem. Technol., 4th edn., Wiley, 1991, 2, 876, (rev)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 207
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, SNN500