Delorazepam

• Catalog No.: Bio-0757
• CAS Number: 2894-67-9
• M. F.: C15H10Cl2N2O
• M. W.: 305.1587

SYNONYMS

• IUPAC name: 7-chloro-5-(2-chlorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one
• IUPAC Traditional name: 7-chloro-5-(2-chlorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one
• Synonyms: 2-Chlorophenyl- N -desmethyldiazepam; Chloronordiazepam; Chlordemethyldiazepam; Briantum; Aurazepam

DATABASE IDS

• CAS Number: 2894-67-9

PROPERTIES

• Application(s): Psychosedatives
• Application(s): Tranquilizers
• Application(s): Parasympatholytic
• Application(s): Ganglionplegic
• Mechanism of Action: Benzodiazepine agonist
• Mechanism of Action: Sympatholytic-alpha
• Mechanism of Action: Heat-regulating centre inhibitor
• Mechanism of Action: Prolactin-release stimulant
• Mechanism of Action: Membranestabilizer
• Mechanism of Action: Dopamine-turnover stimulant
• Mechanism of Action: Dopamine-2-antagonis

REFERENCES

• Ger. Pat., 1974, 2 519 318; CA, 84, 31152, (pivalate)
• Bandoli, G. et al., J.C.S. Perkin 2, 1976, 413, (cryst struct)
• Bogatskii, A.V. et al., Khim.-Farm. Zh., 1977, 11, 85, (synth)
• De Angelis, L., Drugs of Today (Barcelona), 1979, 15, 173, (rev)
• Chananont, P. et al., Acta Cryst. B, 1981, 37, 1371, (cryst struct)
• Quaglio, M.P. et al., Farmaco, Ed. Prat., 1981, 36, 487, (glc)
• Homan, R.W. et al., Antiepileptic Drugs, (Eds. Levy, R. et al), Raven Press, New York, 1989, 841
• Kondo, T. et al., Ther. Drug Monit., 1993, 15, 35, (hplc)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 4330; 4331, (synonyms)
• Jurand, A. et al., Pharmacol. Toxicol., 1994, 74, 228, (tox)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 675