Alrestatin

• Catalog No.: Bio-0756
• CAS Number: 51411-04-2
• M. F.: C14H9NO4
• M. W.: 255.22556

SYNONYMS

• IUPAC name: 2-{2,4-dioxo-3-azatricyclo[7.3.1.0^5,^1^3]trideca-1(13),5,7,9,11-pentaen-3-yl}acetic acid
• IUPAC Traditional name: 2-{2,4-dioxo-3-azatricyclo[7.3.1.0^5,^1^3]trideca-1(13),5,7,9,11-pentaen-3-yl}acetic acid

DATABASE IDS

• CAS Number: 51411-04-2

PROPERTIES

• Application(s): Aldose reductase inhibitor investigated for treatment of diabetic polyneuropathy
• Mechanism of Action: Aldose reductase inhibitor

REFERENCES

• U.S. Pat., 1974, Ayerst McKenna and Harrison, 3 821 383; CA, 81, 176158, (synth, pharmacol)
• Varma, S.D. et al., Science (Washington, D.C.), 1975, 188, 1215, (pharmacol)
• Gabbay, K.H. et al., Metab., Clin. Exp., (Suppl. 1), 1979, 28, 471, (metab)
• El-Naggar, A.M. et al., Egypt. J. Chem., 1981, 24, 127, (synth)
• Humber, L.G., Prog. Med. Chem., 1987, 24, 299, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 277