Ketoprofen

• Catalog No.: Bio-0742
• CAS Number: 22071-15-4
• M. F.: C16H14O3
• M. W.: 254.28056

SYNONYMS

• IUPAC name: 2-(3-benzoylphenyl)propanoic acid
• IUPAC Traditional name: 2-(3-benzoylphenyl)propanoic acid
• Synonyms: Orudis; Alrheumun; Alrheumat; Oruvail

DATABASE IDS

• CAS Number: 22071-15-4

PROPERTIES

• Application(s): Antiinflammatory
• Application(s): Analgesic
• Mechanism of Action: Bradykinin antagonist
• Mechanism of Action: Prostaglandin-antagonist
• Mechanism of Action: Leukotriene synthesis inhibitor

REFERENCES

• Brogden, R.N. et al., Drugs, 1974, 8, 168, (rev, pharmacol)
• Allais, A. et al., Eur. J. Med. Chem. (Chim. Ther.), 1974, 9, 381, (synth, pharmacol)
• Pinna, G. et al., Farmaco, Ed. Sci., 1980, 35, 684, (synth)
• Comisso, G. et al., Gazz. Chim. Ital., 1980, 110, 123, (synth, abs config)
• Liversidge, G.G., Anal. Profiles Drug Subst., 1981, 10, 443, (rev)
• Kim, J.W. et al., Arch. Pharmacal Res., 1987, 10, 25, (resoln, abs config)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 3889
• Mitra, R.B. et al., Synth. Commun., 1988, 18, 2259, (synth)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 21
• Camps, P. et al., Synth. Commun., 1993, 23, 1739, (synth)
• Sonawane, H.R. et al., Tetrahedron, 1994, 50, 1243, (synth)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, BDU500