Nifedipine

• Catalog No.: Bio-0733
• CAS Number: 21829-25-4
• M. F.: C17H18N2O6
• M. W.: 346.33462

SYNONYMS

• IUPAC name: 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC Traditional name: 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• Synonyms: Nimodrel; Adalat; Nifensar XL; Glopir; Procardia; Nifedicor; Adipine; Cardilate; Coracten; Fenihidine; Hypolar Retard; Nifecor; Nifedipress; Nifelat; Nifedotard; Nivaten; Tensipine; Angiopine; Calanif; Calcilat; Coroday; Fortipine; Slofedipine

DATABASE IDS

• CAS Number: 21829-25-4

PROPERTIES

• Application(s): Coronary vasodilator
• Application(s): Antihypertensive agent
• Application(s): Used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon
• Mechanism of Action: Calcium channel blocker
• Mechanism of Action: Inhibits the influx of extracellular calcium through myocardial and vascular membrane pores by physically plugging the channel
• Mechanism of Action: The decrease in intracellular calcium inhibits the contractile processes of smooth muscle cells,
• Mechanism of Action: causing dilation of the coronary and systemic arteries,
• Mechanism of Action: increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

REFERENCES

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