Sulfadimidine

• Catalog No.: Bio-0716
• CAS Number: 57-68-1
• M. F.: C12H14N4O2S
• M. W.: 278.33016

SYNONYMS

• IUPAC name: 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzene-1-sulfonamide
• IUPAC Traditional name: 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzene-1-sulfonamide
• Synonyms: Sulphamezathine; Sulfadimesine; Sulfamethazine; Sulfodimezine; Sulphadimidine; Sulfadimethylpyrimidine; Sulfadimezine; Superseptil; Sulphamethazine; Sulfadimerazine

DATABASE IDS

• CAS Number: 57-68-1

PROPERTIES

• Application(s): Antiseptic
• Application(s): Widely-used, short acting sulfonamide, used in treatment of systemic and urinary tract infections
• Application(s): Low acute toxicity
• Mechanism of Action: Sulfonamides, being structural analogues of para-aminobenzoic acid (PABA), competitively inhibit the incorporation of PABA into dihydropteric acid, the precursor of folic acid.
• Mechanism of Action: Subsequent reduction in the level of folic acid reduced the production of nucleic acids in sensitive bacteria.
• Mechanism of Action: Folate-antagonist
• Mechanism of Action: Dihydrofolate-reductase inhibitor
• Mechanism of Action: Dihydrofolate-synthesis inhibitor

REFERENCES

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