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Ofloxacin

Catalog No. Bio-0713 Name InterBioScreen
CAS Number 82419-36-1 Website http://www.ibscreen.com
M. F. C18H20FN3O4 Telephone +7 49652 40091
M. W. 361.3675032 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 1036

SYNONYMS

IUPAC name
7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
IUPAC Traditional name
7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
Synonyms
Ocuflox
Mefoxacin
Exocin
Tarivid
Flobacin
Oflocet
Oflocin
Oxaldin

DATABASE IDS

CAS Number 82419-36-1

PROPERTIES

Application(s) Antibacterial agent
Application(s) Antiseptic
Application(s) Shows broad spectrum of activity against gram-positive and -negative bacteria
Mechanism of Action DNA gyrase inhibitor

DETAILS

REFERENCES

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  • Eur. Pat., 1982, Daiichi Seiyaku, 47 005; CA, 97, 55821b, (synth, pharmacol)
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  • Egawa, H. et al., Chem. Pharm. Bull., 1986, 34, 4098, (synth)
  • Monk, J.P. et al., Drugs, 1987, 33, 346, (rev)
  • Mitscher, L.A. et al., J. Med. Chem., 1987, 30, 2283, (synth, activity)
  • New Gener. Quinolones, 1990, (Eds. Siporin, C. et al), M. Dekker (see Infect. Dis. Ther. v5 1990), 1990, (book)
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  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 6400; 6401, (synonyms)
  • Hashimoto, K. et al., Acta Cryst. C, 1995, 51, 519
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  • Langtry, H.D. et al., Drugs, 1998, 56, 487-515; 895-928, (rev)
  • Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 221; 233
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, OGI300