Enclomifene

• Catalog No.: Bio-0712
• CAS Number: 15690-57-0
• M. F.: C26H28ClNO
• M. W.: 405.95962

SYNONYMS

• IUPAC name: (2-{4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy}ethyl)diethylamine
• IUPAC Traditional name: (2-{4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy}ethyl)diethylamine
• Synonyms: Clomifene; Cisclomiphene

DATABASE IDS

• CAS Number: 15690-57-0

PROPERTIES

• Application(s): Antiestrogenic
• Application(s): Gonad stimulant
• Mechanism of Action: Gonadotrophin inhibitor
• Mechanism of Action: Estrogen antagonist

REFERENCES

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• Ger. Pat., 1972, 2 224 240; CA, 78, 58036t, (synth)
• Ernst, S. et al., Acta Cryst. B, 1976, 32, 291, (cryst struct)
• Ernst, S. et al., J. Pharm. Sci., 1976, 65, 148, (stereochem)
• Crawley, G.C., Kirk-Othmer Encycl. Chem. Technol., 3rd edn., Wiley, 1978, 12, 658, (rev, pharmacol, tox)
• IARC Monog., 1979, 21, 551; Suppl. 7, 172; Suppl. 6, 184, (rev, tox)
• Clark, J.H. et al., Pharmacol. Ther., 1981, 15, 467, (rev, pharmacol)
• Adashi, E.Y., Fertil. Steril., 1984, 42, 331, (rev)
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• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 7396
• Al-Hassan, M.I., Org. Prep. Proced. Int., 1991, 23, 116, (synth)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1179
• McLeish, M.J. et al., Anal. Profiles Drug Subst., 1998, 25, 85-120, (rev, pharmacol)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CMX500; CMX700