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Mesalazine

Catalog No. Bio-0709 Name InterBioScreen
CAS Number 89-57-6 Website http://www.ibscreen.com
M. F. C7H7NO3 Telephone +7 49652 40091
M. W. 153.13538 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 129

SYNONYMS

IUPAC name
5-amino-2-hydroxybenzoic acid
IUPAC Traditional name
5-amino-2-hydroxybenzoic acid
Synonyms
Asalit
5-aminosalicylic acid
Rowasa
Fisalamine
Mesalamine
Mesalazine
Claversal
Pentasa
Salofalk
Asacol

DATABASE IDS

CAS Number 89-57-6

PROPERTIES

Application(s) Drug used for treatment of ulcerative colitis
Application(s) Esters used as sunscreens
Application(s) Antiinflammatory agent
Application(s) Antiseptic
Application(s) Low acute oral toxicity
Mechanism of Action Cyclooxygenase inhibitor
Mechanism of Action Prostaglandin antagonist

DETAILS

REFERENCES

  • Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 219B, (ir)
  • Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1121C, (nmr)
  • CRC Atlas of Spectral Data and Physical Constants, b848, (ir, uv)
  • Weil, H. et al., Ber., 1922, 55, 2664, (synth)
  • Drain, D.J. et al., J.C.S., 1949, 1498-1503, (N-Ac)
  • Shavel, J. et al., J. Am. Pharm. Assoc., 1953, 42, 402; CA, 48, 9325
  • Lepri, L. et al., J. Chromatogr., 1974, 88, 331
  • Georgieva, M., Anal. Chim. Acta, 1978, 101, 139
  • Hoult, J.R.S., Drugs, 1986, 32, 18, (rev)
  • Myers, B. et al., Gut, 1987, 28, 196, (metab)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 8427
  • Dobson, A.J. et al., Acta Cryst. C, 1998, 54, 1632-1634, (cryst struct)
  • Dash, A.K. et al., Anal. Profiles Drug Subst., 1998, 25, 209-242, (rev, pharmacol)
  • Prakash, A. et al., Drugs, 1999, 57, 383-408, (rev)
  • Clemett, D. et al., Drugs, 2000, 59, 929-956
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AMM500