Fluspirilene

• Catalog No.: Bio-0707
• CAS Number: 1841-19-6
• M. F.: C29H31F2N3O
• M. W.: 475.5727464

SYNONYMS

• IUPAC name: 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• IUPAC Traditional name: 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• Synonyms: Imap; Spirodiflamin; Redeptin

DATABASE IDS

• CAS Number: 1841-19-6

PROPERTIES

• Application(s): Neuroleptic
• Application(s): Psychosedatives
• Mechanism of Action: Calcium channel antagonist
• Mechanism of Action: Dopamine antagonist

REFERENCES

• U.S. Pat., 1966, Janssen, 3 238 216; CA, 65, 8924d, (synth)
• Janssen, P.A.J. et al., Arzneim.-Forsch., 1970, 20, 1689, (pharmacol)
• Blessington, B., Org. Mass Spectrom., 1971, 5, 1113, (ms)
• Kenny, B.A. et al., Br. J. Pharmacol., 1990, 100, 211, (pharmacol)
• Grantham, C.J. et al., Br. J. Pharmacol., 1994, 111, 483, (pharmacol)
• Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 713
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, PFU250