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Haloperidol

Catalog No. Bio-0705 Name InterBioScreen
CAS Number 52-86-8 Website http://www.ibscreen.com
M. F. C21H23ClFNO2 Telephone +7 49652 40091
M. W. 375.8642232 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 385

SYNONYMS

IUPAC name
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
IUPAC Traditional name
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
Synonyms
Haldol
Fortunan
Dozic
Serenace

DATABASE IDS

CAS Number 52-86-8

PROPERTIES

Application(s) Tranquilliser
Application(s) Antipsychotic
Mechanism of Action Dopaminergic antagonist with activity at sigma and NMDA receptors.Also reported to be a potassium channel (IK Ca ) blocker

DETAILS

REFERENCES

  • Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 868B, (nmr)
  • Janssen, P.A.J. et al., J. Med. Chem., 1959, 1, 281, (synth, pharmacol)
  • Harper, N.J. et al., J. Pharm. Pharmacol., 1966, 18, 150, (synth, pharmacol)
  • Blessington, B., Org. Mass Spectrom., 1971, 5, 1113, (ms)
  • Girant, Y. et al., Arch. Int. Pharmacodyn. Ther., 1973, 205, 317, (pharmacol, tox)
  • Janicki, C.A. et al., Anal. Profiles Drug Subst., 1980, 9, 341, (rev)
  • Haloperidol Update 1958-1980, (ed. Ayd, F.J.), Ayd Medical Communications, 1980, (book)
  • Janssen, P.A.J. et al., Handb. Exp. Pharmacol., (Part 1), 1980, 55, 25-41, (pharmacol, rev)
  • Settle, E.C. et al., J. Clin. Psychiatry, 1983, 44, 440, (rev, pharmacol)
  • Azibi, M. et al., J. Pharm. Sci., 1984, 73, 512, (cryst struct, ir)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6089, (synonyms)
  • Froemming, J.S. et al., Clin. Pharmacokinet., 1989, 17, 396, (rev)
  • Park, K.H. et al., J. Chromatogr., 1991, 572, 259, (hplc)
  • Aravagiri, M. et al., J. Chromatogr., B: Biomed. Appl., 1994, 656, 373, (hplc)
  • Ulrich, S. et al., J. Chromatogr., B: Biomed. Appl., 1995, 663, 289, (gc)
  • Fang, J. et al., Psychopharmacology, 1995, 121, 373, (tox)
  • Usuki, E. et al., Chem. Res. Technol., 1996, 9, 800, (metab)
  • Lynch, D.R. et al., J. Pharmacol. Exp. Ther., 1996, 279, 154, (pharmacol)
  • Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 714
  • Hoja, H. et al., J. Chromatogr., B: Biomed. Appl., 1997, 688, 275, (hplc-ms)
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, CLY500; HAG300