Metronidazole

• Catalog No.: Bio-0694
• CAS Number: 443-48-1
• M. F.: C6H9N3O3
• M. W.: 171.15396

SYNONYMS

• IUPAC name: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol
• IUPAC Traditional name: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol
• Synonyms: Zadstat; Torgyl; Midazol; Elyzol; Flagyl; Metrotop

DATABASE IDS

• CAS Number: 443-48-1

PROPERTIES

• Application(s): Antiprotozoal, antibacterial and amoebicidal agent
• Application(s): Treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions:
• Application(s): Amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen)
• Application(s): systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC), bacterial vaginosis
• Application(s): as part of a multidrug regimen for H. pylorieradication to reduce the risk of duodenal ulcer recurrence
• Mechanism of Action: After diffusing into the organism, interacts with DNA to cause a loss of helical DNA structure and strand breakage resulting in inhibition of protein synthesis and cell death in susceptible organisms

REFERENCES

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