Phenylbutazone

• Catalog No.: Bio-0693
• CAS Number: 50-33-9
• M. F.: C19H20N2O2
• M. W.: 308.3743

SYNONYMS

• IUPAC name: 4-butyl-1,2-diphenylpyrazolidine-3,5-dione
• IUPAC Traditional name: 4-butyl-1,2-diphenylpyrazolidine-3,5-dione
• Synonyms: Flexazone; Phenbutazone; Butapirazole; Butazolidin; Diphenylbutazone; Butadion; Butacote; Butalidon; Fenylbutazon

DATABASE IDS

• CAS Number: 50-33-9

PROPERTIES

• Application(s): Analgesic
• Application(s): Antipyretic
• Application(s): Antiinflammatory, esp. antirheumatic
• Application(s): Use limited due to toxicity
• Mechanism of Action: Prostaglandin antagonist

REFERENCES

• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1449A, (nmr)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 400C, (ir)
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• Mondelli, R. et al., Gazz. Chim. Ital., 1965, 95, 1371, (pmr)
• Locock, R.A. et al., J. Pharm. Sci., 1974, 63, 1896, (ms)
• IARC Monog., 1977, 13, 183; Suppl. 7, 316; Suppl. 6, 459, (rev, tox)
• Davies, D.S., J. Int. Med. Res., (Suppl. 2), 1977, 5, 15, (rev, metab)
• Singh, T.P. et al., J.C.S. Perkin 2, 1977, 693, (cryst struct)
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• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 29
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, BRF500