Home > Compound List > Product Information
Curcumin_Molecular_structure_CAS_458-37-7)
Click picture or here to close

Curcumin

Catalog No. Bio-0677 Name InterBioScreen
CAS Number 458-37-7 Website http://www.ibscreen.com
M. F. C21H20O6 Telephone +7 49652 40091
M. W. 368.3799 Fax
Purity Email screen@ibscreen.chg.ru
Storage Chembase ID: 81908

SYNONYMS

IUPAC name
(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
IUPAC Traditional name
(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
Synonyms
Curcuma yellow
Diferuloylmethane

DATABASE IDS

CAS Number 458-37-7

PROPERTIES

Application(s) Antiinflammatory agent
Application(s) Antitumor
Application(s) Antiarthritic
Application(s) Antiamyloid
Application(s) Bile stimulant showing hepatoprotective props
Application(s) Possesses bactericidal and fungicidal props.
Biological Source Isol. from Curcuma zedoaria (turmeric), other Curcuma spp. and other spp.
Description Tautomers
Mechanism of Action Inhibitor of eicosanoid biosynthesis
Mechanism of Action Acts as a free radical scavenger and antioxidant, inhibiting lipid peroxidation and oxidative DNA damage
Mechanism of Action Induce glutathione S-transferase and are potent inhibitors of cytochrome P450;

DETAILS

REFERENCES

  • Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 52C, (ir)
  • Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 800B, (nmr)
  • Lampe, V., Ber., 1918, 51, 1347, (synth)
  • Srinivasan, K.R., J. Pharm. Pharmacol., 1953, 5, 448, (derivs)
  • Spicer, G.S. et al., Anal. Chim. Acta, 1958, 18, 231, (detn, B)
  • Umland, F. et al., Fresenius' Z. Anal. Chem., 1963, 197, 151, (detn, Ni)
  • Jentzsch, K. et al., Sci. Pharm., 1968, 36, 251; CA, 70, 90793h, (isol)
  • Sastry, B.S., Res. Ind., 1970, 15, 258; CA, 75, 75063e, (isol)
  • Kuroyagi, M. et al., Yakugaku Zasshi, 1970, 90, 1467; CA, 74, 61612a, (isol)
  • Dyrssen, D.W. et al., Anal. Chim. Acta, 1972, 60, 139, (detn, B)
  • Roughley, P.J. et al., J.C.S. Perkin 1, 1973, 2379-2388, (biosynth)
  • Karig, F., Dtsch. Apoth. -Ztg., 1975, 115, 325; CA, 83, 65372f, (derivs)
  • Quint, P. et al., Fresenius' Z. Anal. Chem., 1977, 285, 356; 1979, 295, 269, (detn, B)
  • Kashina, C. et al., Heterocycles, 1977, 7, 241, (synth)
  • Wahlstrom, B. et al., Acta Pharmacol. Toxicol., 1978, 43, 86, (metab)
  • Holder, G.M. et al., Xenobiotica, 1978, 8, 761, (metab)
  • Tonnesen, H.H. et al., Acta Chem. Scand., Ser. B, 1982, 36, 475, (cryst struct, bibl)
  • Cheng, K.L. et al., Handbook of Organic Analytical Reagents, CRC Press, Boca Raton, 1982, 511, (use)
  • Ammon, H.P.T. et al., Planta Med., 1991, 57, 1-7, (rev, pharmacol)
  • Jitoe, A. et al., J. Agric. Food Chem., 1992, 40, 1337-1340, (occur)