Prednisolone trimethylacetate

• Catalog No.: Bio-0674
• CAS Number: 1107-99-9
• M. F.: C26H36O6
• M. W.: 444.56044

SYNONYMS

• IUPAC name: 2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethyl 2,2-dimethylpropanoate
• IUPAC Traditional name: 2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethyl 2,2-dimethylpropanoate
• Synonyms: Ultracortenol; Ultracorterenol; Mecortolon; Vecortenol

DATABASE IDS

• CAS Number: 1107-99-9

PROPERTIES

• Application(s): Antiinflammatory
• Application(s): Antiallergic agent
• Application(s): Immunosuppressive
• Mechanism of Action: Adrenocortical steroid
• Mechanism of Action: ACTH antagonist
• Mechanism of Action: ACTH secretion inhibitor
• Mechanism of Action: Gluconeogenesis promoter
• Mechanism of Action: Phosphorus mobilizer.
• Mechanism of Action: Glycogen deposition inhibitor
• Mechanism of Action: Calcium mobilizer

REFERENCES

• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 585B, (nmr)
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• Herzog, H.L. et al., Tetrahedron, 1962, 18, 581, (synth)
• Hirschmann, R. et al., J.A.C.S., 1964, 86, 3903, (synth)
• Toft, P. et al., Can. J. Spectrosc., 1970, 15, 137, (ms)
• Gambertoglis, J.G. et al., J. Pharmacokinet. Biopharm., 1980, 8, 1, (rev, pharmacol)
• Jusko, W.J. et al., Ther. Drug Monit., 1980, 2, 169, (rev, pharmacol)
• Gonzalez, M.D. et al., Org. Magn. Reson., 1984, 22, 586, (cmr)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6297; 6321; 6941
• Kirk, D.N. et al., J.C.S. Perkin 2, 1990, 1567, (pmr)
• Ali, S.L., Anal. Profiles Drug Subst., 1992, 21, 415, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 737
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AAF625; PMA000; PMA100; SOV100; PLY300