Simvastatin

• Catalog No.: Bio-0672
• CAS Number: 79902-63-9
• M. F.: C25H38O5
• M. W.: 418.56622

SYNONYMS

• IUPAC name: (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
• IUPAC Traditional name: (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
• Synonyms: Zocord; Lipex; Synvinolin; Lodales; Denan; Zocor; Sinvacor; Colemin; Liponorm; Medipo; Pantok; Sivastin; Velastatin

DATABASE IDS

• CAS Number: 79902-63-9

PROPERTIES

• Application(s): Antiarteriosclerotic
• Application(s): Used in the treatment of hypercholesterolaemia, and to reduce risk of death in patients with coronary heart disease and high serum cholesterol levels
• Biological Source: Metab. of Aspergillus terreus and Monascus spp.*
• Mechanism of Action: HMG-CoA reductase inhibitor
• Mechanism of Action: Increases HDL cholesterol levels
• Mechanism of Action: Decreases LDL cholesterol levels, VLDL cholesterol levels and plasma triglycerides
• Mechanism of Action: Cholesterol synthesis inhibitor

REFERENCES

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