Prednisolone hemisuccinate

• Catalog No.: Bio-0671
• CAS Number: 2920-86-7
• M. F.: C25H32O8
• M. W.: 460.51678

SYNONYMS

• IUPAC name: 4-{2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethoxy}-4-oxobutanoic acid
• IUPAC Traditional name: 4-{2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethoxy}-4-oxobutanoic acid

DATABASE IDS

• CAS Number: 2920-86-7

PROPERTIES

• Mechanism of Action: ACTH antagonist
• Mechanism of Action: ACTH secretion inhibitor
• Mechanism of Action: Gluconeogenesis promoter
• Mechanism of Action: Glycogen deposition inhibitor
• Mechanism of Action: Calcium mobilizer
• Mechanism of Action: Phosphorus mobilizer
• Mechanism of Action: Glucocorticoid
• Application(s): Antiinflammatory,
• Application(s): Immunosuppressive
• Application(s): Antiallergic agent

REFERENCES

• McAleer, W.J. et al., J.O.C., 1958, 23, 508, (synth)
• Smith, L.L. et al., J.O.C., 1958, 23, 960, (spectra)
• Pechet, M.M. et al., J. Colloid Sci., 1959, 38, 681, (pharmacol)
• Herzog, H.L. et al., Tetrahedron, 1962, 18, 581, (synth, ir, pmr, uv)
• Gladiali, S. et al., Chem. Ind. (London), 1977, 982, (synth)
• Martindale, The Extra Pharmacopoeia, 28th/29th edn., Pharmaceutical Press, 1982, 12869