Isoflupredone

• Catalog No.: Bio-0670
• CAS Number: 338-95-4
• M. F.: C21H27FO5
• M. W.: 378.4344832

SYNONYMS

• IUPAC name: (1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• IUPAC Traditional name: (1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• Synonyms: 9-Fluoroprednisolone; Deltafludrocortisone

DATABASE IDS

• CAS Number: 338-95-4

PROPERTIES

• Application(s): Antiinflammatory agent
• Application(s): Immunosuppressive
• Mechanism of Action: Adrenocorticosteroid
• Mechanism of Action: ACTH antagonist
• Mechanism of Action: ACTH secretion inhibitor
• Mechanism of Action: Gluconeogenesis promoter
• Mechanism of Action: Glycogen deposition inhibitor
• Mechanism of Action: Calcium mobilizer
• Mechanism of Action: Phosphorus mobilizer

REFERENCES

• McAleer, W.J. et al., J.O.C., 1958, 23, 508, (synth)
• Smith, L.L. et al., J.O.C., 1958, 23, 960, (spectra)
• Pechet, M.M. et al., J. Colloid Sci., 1959, 38, 681, (pharmacol)
• Herzog, H.L. et al., Tetrahedron, 1962, 18, 581, (synth, ir, pmr, uv)
• Gladiali, S. et al., Chem. Ind. (London), 1977, 982, (synth)
• Martindale, The Extra Pharmacopoeia, 28th/29th edn., Pharmaceutical Press, 1982, 12869