Prednisolone

• Catalog No.: Bio-0666
• CAS Number: 50-24-8
• M. F.: C21H28O5
• M. W.: 360.44402

SYNONYMS

• IUPAC name: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• IUPAC Traditional name: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• Synonyms: Hydeltra; Delta-Cortef; 1-Dehydrocortisol

DATABASE IDS

• CAS Number: 50-24-8

PROPERTIES

• Mechanism of Action: On binding, the corticoreceptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes.
• Mechanism of Action: The DNA bound receptor then interacts with basic transcription factors, causing an increase or decrease in expression of specific target genes, including suppression of IL2 (interleukin 2) expression.
• Mechanism of Action: Glucocorticoid receptor agonist.
• Application(s): Adrenergic agent
• Application(s): Antiinflammatory agent
• Application(s): Antineoplastic agent

REFERENCES

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