Triamcinolone

• Catalog No.: Bio-0662
• CAS Number: 124-94-7
• M. F.: C21H27FO6
• M. W.: 394.4338832

SYNONYMS

• IUPAC name: (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• IUPAC Traditional name: (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• Synonyms: Lederspan; Aristocort; Kenacort; Fluoxiprednisolone; Volon

DATABASE IDS

• CAS Number: 124-94-7

PROPERTIES

• Application(s): Antiinflammatory agent
• Application(s): Immunosuppressive
• Mechanism of Action: Glucocorticoid
• Mechanism of Action: ACTH antaganist
• Mechanism of Action: ACTH secretion inhibitor
• Mechanism of Action: Phosphorus mobilizer
• Mechanism of Action: Glycogen deposition inhibitor
• Mechanism of Action: Gluconeogenesis promoter
• Mechanism of Action: Calcium mobilizer
• Mechanism of Action: Immunosuppressive

REFERENCES

• Toft, P. et al., Can. J. Pharm. Sci., 1972, 7, 53, (ms)
• Fiegel, G., Arzneim.-Forsch., 1975, 25, 560, (rev)
• Zbinovsky, V. et al., Anal. Profiles Drug Subst., 1977, 6, 579, (rev)
• Sieh, D.H., Anal. Profiles Drug Subst., 1982, 11, 593; 615; 651, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6222; 7100; 7152
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 739
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AQX250; AQY375; AQX500; AQX750
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 586B, (nmr)
• Bernstein, S. et al., J.A.C.S., 1956, 78, 5693, (synth)
• Fried, J. et al., J.A.C.S., 1958, 80, 2338, (synth, pharmacol)
• Florey, K., Anal. Profiles Drug Subst., 1972, 1, 367; 397; 423, (rev)