Cortodoxone cortifen

• Catalog No.: Bio-0650
• CAS Number: 152-58-9
• M. F.: C21H30O4
• M. W.: 346.4605

SYNONYMS

• IUPAC name: (1S,2R,10R,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC Traditional name: (1S,2R,10R,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one

DATABASE IDS

• CAS Number: 152-58-9

PROPERTIES

• Application(s): Antiinflammatory drug
• Application(s): Immunosuppressive
• Biological Source: Found in the blood and urine of humans and other mammals
• Mechanism of Action: Glucocorticoid
• Mechanism of Action: ACTH antagonist
• Mechanism of Action: ACTH secretion inhibitor
• Mechanism of Action: Gluconeogenesis promoter
• Mechanism of Action: Glycogen deposition inhibitor
• Mechanism of Action: Calcium mobilizer
• Mechanism of Action: Phosphorus mobilizer

REFERENCES

• Aldrich Library of 13C and 1H FT NMR Spectra , 1992, 3 , 584B, (nmr)
• Aldrich Library of FT-IR Spectra, 1st edn. , 1985, 2 , 1054C, (ir)
• Reichstein, T. et al. , Helv. Chim. Acta , 1938, 21 , 1197, (isol, synth)
• Gallagher, T.F. et al. , J.A.C.S. , 1949, 71 , 3262, (synth)
• Julian, P.L. et al. , J.A.C.S. , 1950, 72 , 5145, (synth)
• Smit, A. et al. , Rec. Trav. Chim. (J. R. Neth. Chem. Soc.) , 1966, 85, 731, (synth)
• Dupont, L. et al. , Acta Cryst. , 1973, 29 , 205, (cryst struct)
• Boar, R.B. , J.C.S. Perkin 1 , 1975, 1275, (pmr)
• Tseikinskii, V.M. et al. , Bioorg. Khim. , 1979, 5 , 1537, (cryst struct)
• Gonzalez, M.D. et al. , Org. Magn. Reson. , 1984, 22 , 586, (cmr)
• Numazawa, M. et al. , J.O.C. , 1985, 50 , 81, (synth)