Prednisolone acetate

• Catalog No.: Bio-0646
• CAS Number: 52-21-1
• M. F.: C23H30O6
• M. W.: 402.4807

SYNONYMS

• IUPAC name: 2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethyl acetate
• IUPAC Traditional name: 2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethyl acetate
• Synonyms: Supercortyl; Inflanefran Forte; Prednelan; Nisolone; Cormalone; Cortipred

DATABASE IDS

• CAS Number: 52-21-1

PROPERTIES

• Application(s): Antiinflammatory agent
• Application(s): Immunosuppressive
• Mechanism of Action: ACTH antagonist
• Mechanism of Action: ACTH secretion inhibitor
• Mechanism of Action: Phosphorus mobilizer
• Mechanism of Action: Glycogen deposition inhibitor
• Mechanism of Action: Gluconeogenesis promoter
• Mechanism of Action: Calcium mobilizer
• Mechanism of Action: Corticosteroid

REFERENCES

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• Poos, G.I. et al., Chem. Ind. (London), 1958, 1260, (phosphate)
• Hirschmann, R. et al., J.A.C.S., 1964, 86, 3903, (synth)
• Toft, P. et al., Can. J. Spectrosc., 1970, 15, 137, (ms)
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• Kirk, D.N. et al., J.C.S. Perkin 2, 1990, 1567, (pmr)
• Ali, S.L., Anal. Profiles Drug Subst., 1992, 21, 415, (rev)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 737
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AAF625; PMA000; PMA100; SOV100; PLY300