Etofylline

• Catalog No.: Bio-0641
• CAS Number: 519-37-9
• M. F.: C9H12N4O3
• M. W.: 224.21658

SYNONYMS

• IUPAC name: 7-(2-hydroxyethyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• IUPAC Traditional name: 7-(2-hydroxyethyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• Synonyms: Phyllocormin N; Bio-phylline; Oxytheonyl; Oxphylline; Theostat

DATABASE IDS

• CAS Number: 519-37-9

PROPERTIES

• Application(s): Diuretic
• Application(s): Vasodilator
• Application(s): Cardiant
• Mechanism of Action: Phosphodiesterase inhibitor
• Mechanism of Action: Purine antagonist
• Mechanism of Action: Prostaglandin antagonist
• Mechanism of Action: CNS-stimulant

REFERENCES

• Taugner, R. et al., Arzneim.-Forsch., 1956, 6, 601, (pharmacol)
• Roth, H.J., Arch. Pharm. (Weinheim, Ger.), 1959, 292, 234, (synth)
• Schlemmer, W., J. Chromatogr., 1971, 63, 121, (tlc)
• Kamei, K. et al., Chem. Pharm. Bull., 1973, 21, 1228, (glc, ms)
• Ostrovska, V. et al., J. Liq. Chromatogr., 1989, 12, 2793, (metab, hplc)
• Biagi, G.L. et al., J. Chromatogr., 1990, 498, 179, (tlc)
• Franzone, J.S. et al., Methods Find. Exp. Clin. Pharmacol., 1991, 13, 289, (pharmacol, tox)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1318
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 1511, (synonyms)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, HLC000