Betamethasone dipropionate

• Catalog No.: Bio-0632
• CAS Number: 5593-20-4
• M. F.: C28H37FO7
• M. W.: 504.5875832

SYNONYMS

• IUPAC name: 2-[(1R,2S,10S,11S,13S,14R,15S,17S)-1-fluoro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-(propanoyloxy)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethyl propanoate
• IUPAC Traditional name: 2-[(1R,2S,10S,11S,13S,14R,15S,17S)-1-fluoro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-(propanoyloxy)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethyl propanoate
• Synonyms: Diprosone

DATABASE IDS

• CAS Number: 5593-20-4

PROPERTIES

• Application(s): Antiinflammatory
• Application(s): Immunosuppressive
• Mechanism of Action: ACTH secretion inhibitor
• Mechanism of Action: Glycogen deposition inhibitor
• Mechanism of Action: Gluconeogenesis promoter
• Mechanism of Action: Calcium mobilizer
• Mechanism of Action: Corticosteroid

REFERENCES

• Oliveto, E.P. et al., J.A.C.S., 1958, 80, 6687, (synth)
• Taub, D. et al., J.A.C.S., 1960, 82, 4012, (synth)
• Carrington, T.R. et al., J.C.S., 1961, 4560, (synth)
• Rausser, R. et al., J.O.C., 1966, 31, 26, (synth)
• Scapagnini, U. et al., Curr. Ther. Res., Clin. Exp., 1968, 10, 464, (pharmacol)
• Merrill, E.J. et al., J. Labelled Compd., 1971, 7, 509, (synth)
• Ferrante, M.G. et al., Anal. Profiles Drug Subst., 1977, 6, 43, (rev, dipropionate)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6645; 6676; 7580, (synonyms)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 724
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, BFV765; BFV770; VCA000